Neuromuscular diseases

Duchenne & Becker Muscular Dystrophies

Duchenne and Becker Muscular Dystrophies (DMD & BMD) are X-linked (usually only boys are affected) recessive neuromuscular disorders affecting approximately 1 in 3,500 and 1 in 30,000 live male births, respectively.

DMD and BMD are both characterized by progressive symmetrical muscular weakness. DMD symptoms typically present before age five wheras the milder BMD may not be diagnosed until later.

Both DMD and BMD are caused by mutations in the dystrophin gene. The human dystrophin gene is the largest human gene, found on the X chromosome and occupying roughly 0.1% of the genome. 

Further information about Duchenne and Becker Muscular Dystrophies can be found on the Muscular Dystrophy Campaign website.

DMD

BMD

 




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